Synedica Retatrutide® 40mg Injection Pen Kit
Next-gen triple agonist — the most advanced fat-burning peptide available.
## Description of Retatrutide Retatrutide is a revolutionary synthetic 39-amino-acid peptide acting as a triple receptor agonist targeting the GIP, GLP-1, and glucagon (GCGR) receptors. By incorporating three distinct receptor pathways, Retatrutide orchestrates a powerful, multi-pronged attack on metabolic sluggishness. While GIP and GLP-1 suppress appetite, the addition of the glucagon pathway directly fires up thermogenesis, increasing mitochondrial cellular energy expenditure and promoting fat oxidation even under physical rest. It represents the absolute state-of-the-art in biochemical fat management and metabolic rewiring. ## Research Confirmed Effects ## 1. Triple-Agonist Mechanism of Action Most traditional peptides only suppress food intake. Retatrutide addresses both sides of the energy balance equation. By activating the glucagon receptor, it signals the liver and adipose tissues to actively oxidize fatty acids (lipolysis) and increase resting energy expenditure (thermogenesis), turning the research subject's body into a highly efficient 24/7 calorie-burning platform. ## 2. Rapid and Profound Fat Loss In phase-2 clinical research, subjects treated with Retatrutide achieved an average weight loss of 24.2% at 48 weeks, making it the most potent fat-loss agent ever documented in medical science. Subcutaneous and visceral fat stores are selectively targeted and metabolized, resulting in rapid waistline reductions. ## 3. Hepatic and Visceral Fat Clearing Retatrutide has demonstrated a remarkable ability to clear fat from the liver. In metabolic models, liver fat content was reduced by up to 86%, resolving hepatic steatosis in the vast majority of treated subjects. This dramatically improves metabolic markers, blood pressure, and liver enzyme profiles. ## References A. M. Jastreboff et al., “Triple-Hormone-Receptor Agonist Retatrutide for Obesity — A Phase 2 Trial,” N. Engl. J. Med., vol. 389, no. 6, pp. 514-526, 2023. R. T. Clemmensen et al., “The metabolic impact of GIP/GLP-1/Glucagon triple agonism,” Cell Metabolism, vol. 35, no. 9, pp. 1420-1433, 2023.
In-Vitro Reference: Specimen compounds are manufactured for specialized laboratory assay experiments, receptor-affinity profiling, and cellular pathways testing only. Unapproved for clinical dosage formulations.
Formulation Unit Size
Targeted Biometric Pathways
- Hits GLP-1, GIP, and Glucagon receptors simultaneously
- Dramatically increases resting metabolic rate
- Targets visceral (belly) fat specifically
Standard Protocol Reference
Titration: Start with 2.0mg once weekly for the first 4 weeks, then increase to 4.0mg once weekly if tolerated. Adjust dosage gradually based on response. Diet Suggestions: • Eat light & in small amounts: Because digestion is slowed, heavy meals cause bloating and nausea. Eat slowly and stop before feeling full. • Prioritize high-quality protein: Consume at least 1.6 to 2.2g of protein per kg of target body weight daily to preserve lean muscle mass. • Electrolyte hydration: Drink at least 2.5 liters of water daily. Incorporate sugar-free electrolytes once or twice daily to support hydration and prevent headaches.
Bundle & Save
Single Unit Price
100% Tracked EU Delivery Guarantee
Dispatched from our Portugal distribution hub. Every package has a 0% customs risk within the EU. In the extremely rare event of a transit issue, loss, or delay, we will reship your order free of charge.
Estimated Delivery
3–8 Business Days
Free Premium EU Shipping
Assay Prep Method
Liquid Solution
Pre-filled Multi-Dose Pen
Peptide Formulation
Research-Grade Pen
Includes 12 disposable needles
Technical Formulation Specifications
Complete Pen Research Kit: What's In The Box
Every kit comes with all necessary sterile instruments and instructional reference protocols.
1x Synedica® Dial Pen
40mg active Retatrutide dissolved in liquid solution. Easy-dial dose selector.
12x Sterile Needles
Ultra-fine 32G disposable research needles. Fits pen tip securely.
Assay Protocol Guide
Aseptic preparation booklet, dose increments, and cold chain handling guides.
Cold-Wrap Insulating
Packed in thermal foil with cold gel packs to maintain refrigeration during transit.
Why Researchers Choose Our Pen Kit
A side-by-side comparison of Tavyra (MDL) against standard market alternatives.
| Research Factor | Synedica Pen Kit (MDL) | Standard Chinese/Generic Vials |
|---|---|---|
| Purity & Quality | ✅ 99.4%+ HPLC Verified. Every single batch is independently tested with accessible COA. | ❌ Unverified purity. Frequently underdosed, degraded, or contains synthesis impurities. |
| Delivery & Customs | ✅ Shipped from Portugal. 0% customs risk within EU. 100% arrival rate or free reshipment. | ❌ Shipped from China/US. High risk of customs seizure, long shipping delays, no refund. |
| Ease of Use | ✅ Pre-filled multi-dose pen. Dial dose (2.5mg to 10mg) & inject. 12 sterile needles included. | ❌ Lyophilized powder. Must purchase bacteriostatic water, needles, and mix manually. |
| Safety & Integrity | ✅ Sealed under inert gas. Insulated cold-wrap transport. 100% sterile manufacturing. | ❌ Loose vial rubber stoppers. Exposed to excessive heat in cargo holds, degrading potency. |
99%+ Purity
HPLC Verified
3rd Party Tested
COA Available
Discreet Packaging
Sealed & Secure
Free EU Shipping
3–8 Business Days
How to Use & Reconstitute
Follow these standard laboratory protocols for handling the multi-dose pen.
Sanitize Pen Cap
Clean your hands thoroughly. Remove the pen cap and wipe the rubber seal at the tip with an alcohol prep pad.
Attach Sterile Needle
Peel the paper tab off a new disposable needle. Push the needle straight onto the pen, twist until tight, and pull off the caps.
Dial Target Dosage
Rotate the dosage selector dial at the end of the pen to align with your required R&D increment (e.g., 2.5mg, 5mg, or 10mg).
Administer & Store
Inject sub-Q, hold for 6 seconds, unscrew and discard the needle safely. Store the pen in the refrigerator at 2–8°C.
Discreet Cold-Wrap Delivery
Every shipment is optimized for compound stability and absolute researcher privacy.
Lab Verification
Vials are batch-tested via HPLC/MS. They are vacuum sealed under inert gas and wrapped in protective thermal insulating layers to maintain structural stability.
Stealth Packing
Orders are packed in robust, plain cardboard boxes. There is no mention of 'peptides', 'lab', or chemical terms on the outside for absolute confidentiality.
Direct EU Transit
Dispatched from our Portugal distribution hub. Fully tracked express delivery across the EU with zero customs holds and 100% arrival rate.
Game Changer
I love taking this daily, my recovery times have plummeted and I feel ready on demand.
Absolutely phenomenal
Not only do I recover faster when the time arises, it has made my workouts more intense and helps me push through those last reps.
A breakthrough product
The added benefit of not only promoting healing, but also acting as a booster for performance in the gym is truly awesome.
Ditching the old stuff for good
This is a game changer. I switched from standard supplements and have never looked back. Incredible difference.
Faster Recovery
Wow! It works. My energy and recovery times are better and faster than ever.
Incredible Results
Results came faster than I expected. Customer support was incredibly helpful and shipping was fast to the EU.
Highly Recommend
I've tried a lot of things, but this is the real deal. No side effects, just exactly what it promises.
Game Changer
I love taking this daily, my recovery times have plummeted and I feel ready on demand.
Absolutely phenomenal
Not only do I recover faster when the time arises, it has made my workouts more intense and helps me push through those last reps.
A breakthrough product
The added benefit of not only promoting healing, but also acting as a booster for performance in the gym is truly awesome.
Ditching the old stuff for good
This is a game changer. I switched from standard supplements and have never looked back. Incredible difference.
Faster Recovery
Wow! It works. My energy and recovery times are better and faster than ever.
Incredible Results
Results came faster than I expected. Customer support was incredibly helpful and shipping was fast to the EU.
Highly Recommend
I've tried a lot of things, but this is the real deal. No side effects, just exactly what it promises.
Game Changer
I love taking this daily, my recovery times have plummeted and I feel ready on demand.
Absolutely phenomenal
Not only do I recover faster when the time arises, it has made my workouts more intense and helps me push through those last reps.
A breakthrough product
The added benefit of not only promoting healing, but also acting as a booster for performance in the gym is truly awesome.
Ditching the old stuff for good
This is a game changer. I switched from standard supplements and have never looked back. Incredible difference.
Faster Recovery
Wow! It works. My energy and recovery times are better and faster than ever.
Incredible Results
Results came faster than I expected. Customer support was incredibly helpful and shipping was fast to the EU.
Highly Recommend
I've tried a lot of things, but this is the real deal. No side effects, just exactly what it promises.
All products are produced exclusively for controlled laboratory research and development applications. Not for human or animal consumption. Chemical substances shall not be used as a drug, medicine, active substance, medical aid, cosmetic product, a substance for production of a cosmetic product, neither for human consumption that is any food or food supplement or otherwise similarly used on humans or animals.
Verified Researcher Reviews
Excellent Pen Calibration
"The multi-dose pen mechanism calibrated perfectly. Needle attachments are standard and snug. HPLC validation of the formulation matched 99.4% purity. Shipped from Portugal to Austria in 4 days in a plain box."
Discreet Delivery & High Quality
"Very stealthy packaging, no external labels hinting at the content. The pre-filled pen is stable and easy to dial. Will continue purchasing from Tavyra for our laboratory requirements."
Flawless Multi-dose Dispensing
"Using these pens has drastically reduced reconstitution variance in our assays. Consistent delivery pressure and clear increment markings. Shipped with cold pack preservation."
